The
mode by which the synthesis of an enzyme is prevented by
repressor molecules. In many cases, the end product of a synthesis chain (e.g. an amino acid)
acts as a feed-back corepressor by combining with an intracellular aporepressor protein,
so that this complex is able to
block the function of an operator. As a result, the whole
operon is prevented from being transcribed into
mRNA, and the expression of all
enzymes necessary for the synthesis of the end product amino acid is abolished.
Source:
PAC, 1992, 64, 143
(Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992))
on page 152
Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
https://doi.org/10.1351/goldbook.
