Endonucleases which recognize specific base sequences within a
DNAhelix, creating a double-strand break of
DNA. Type I restriction
enzymes bind to these
recognition sites but subsequently cut the
DNA at different sites. Type II restriction
enzymes both bind and cut within their recognition or target sites.
Source:
PAC, 1992, 64, 143
(Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992))
on page 164