A
stereoheterotopic group
c
(as in tetrahedral
Xabc2)
is described as
pro-R if, when it is arbitrarily assigned
CIP priority over the other
stereoheterotopic group
c, the configuration of the thus generated
chiral centre is assigned the
stereodescriptorR.
The other group
c is then described as
pro-S. This method for distinguishing between
stereoheterotopic groups can be applied to other kinds of prochiral molecular entities or
prochiral parts of molecular entities considered on their own.
Source:
PAC, 1996, 68, 2193
(Basic terminology of stereochemistry (IUPAC Recommendations 1996))
on page 2214
Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
https://doi.org/10.1351/goldbook.
