Lowest concentration or
amount of a substance, found by experiment or observation, which
causes an adverse alteration of
morphology, functional capacity,
growth, development, or life span of a target organism distinguishable
from normal (control) organisms of the same species and
strain under
defined conditions of
exposure.
Source:
PAC, 1993, 65, 2003
(Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993))
on page 2065
PAC, 2001, 73, 993
(Risk assessment for occupational exposure to chemicals. A review of current methodology
(IUPAC Technical Report))
on page 1023
Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
https://doi.org/10.1351/goldbook.
