Structure-based design is a design strategy for new chemical entities
based on the three-dimensional (
3D) structure of the target obtained
by X-ray or nuclear magnetic
resonance (
NMR) studies, or from
protein homology models.
Source:
PAC, 1997, 69, 1137
(Glossary of terms used in computational drug design (IUPAC Recommendations 1997))
on page 1150