Greatest concentration or amount
found by experiment or observation, which causes no
detectable adverse alteration of
morphology, functional capacity,
growth, development, or life span of the target organism under
defined conditions.
Source:
PAC, 1993, 65, 2003
(Glossary for chemists of terms used in toxicology (IUPAC Recommendations 1993))
on page 2076
PAC, 2001, 73, 993
(Risk assessment for occupational exposure to chemicals. A review of current methodology
(IUPAC Technical Report))
on page 1023
This definition replaces an earlier definition of no-observed-adverse-effect-level (NOAEL).