In
competitive binding assays, the logit-log
dose relationship, in which the response is defined by:
where
with
=
fraction of
tracer bound and
= value of
with no unlabelled
ligand in the system. Logit transformed
assay data frequently yield straight-line
dose-response curves, amenable to statistical analysis.
Source:
PAC, 1994, 66, 2513
(Nomenclature for radioanalytical chemistry (IUPAC Recommendations 1994))
on page 2522