A phenomenon whereby the
conformation of an
enzyme or other protein is altered by combination, at a site other than the substrate-
binding site, with a small molecule, referred to as an
effector, which results in either increased or decreased activity by the enzyme.
Source:
PAC, 1994, 66, 2587
(Glossary of bioanalytical nomenclature - Part 1: General terminology, body fluids,
enzymology, immunology (IUPAC Recommendations 1994))
on page 2593