The
acceleration of a chemical
transformation at one site of a
molecular entity through the involvement of another
functional ('catalytic') group in the same molecular entity, without that group appearing to have undergone change
in the reaction product. The use of the term should be restricted to cases for which
analogous
intermolecularcatalysis by
chemical species bearing that catalytic group is observable.
Intramolecularcatalysis can be detected and expressed in quantitative form by a comparison of the reaction
rate with that of a comparable model compound in which the catalytic group is absent,
or by measurement of the
effective molarity of the catalytic group.
Source:
PAC, 1994, 66, 1077
(Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994))
on page 1126
Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
https://doi.org/10.1351/goldbook.
