The volume of the mobile phase (or the corresponding time) required to
elute a component the concentration of which in the stationary phase is negligible compared
to that in the mobile phase. In other words, this component is not retained at all
by the stationary phase. Thus, the hold-up volume (time) is equal to the retention
volume (time) of an unretained compound. The hold-up volume (time) includes any volumes
contributed by the sample injector, the detector, and connectors.
In gas
chromatography this term is also called the gas hold-up volume (time). The corrected gas hold-up
volume
(
) is the gas hold-up volume multiplied by the compression (compressibility) correction
factor
(
):
Assuming that the influence of extra column volume on
is negligible,
Source:
PAC, 1993, 65, 819
(Nomenclature for chromatography (IUPAC Recommendations 1993))
on page 841
Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
https://doi.org/10.1351/goldbook.
,
