Fe2+ + H2O2
Fe3+ + OH. + OH−.
This is the iron-
salt-dependent
decomposition of dihydrogen peroxide, generating the highly reactive
hydroxyl radical, possibly
via an oxoiron(IV) intermediate. Addition
of a reducing agent, such as ascorbate, leads to a cycle which
increases the damage to biological molecules.
Source:
PAC, 1997, 69, 1251
(Glossary of terms used in bioinorganic chemistry (IUPAC Recommendations 1997))
on page 1274
Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
https://doi.org/10.1351/goldbook.
