Member of a superfamily of heme-containing monooxygenases
involved in
xenobioticmetabolism, cholesterol
biosynthesis, and
steroidogenesis, in eukaryotic organisms found mainly in the
endoplasmic reticulum and inner mitochondrial
membrane of cells.
‘P450’ refers to a feature in the carbon monoxide absorption
difference spectrum at
caused by the presence of a thiolate in
the axial position of the heme opposite to the carbon monoxide
ligand.
Source:
PAC, 2004, 76, 1033
(Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003))
on page 1048
Cite as:
IUPAC. Compendium of Chemical Terminology, 2nd ed. (the "Gold Book"). Compiled by
A. D. McNaught and A. Wilkinson. Blackwell Scientific Publications, Oxford (1997).
XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic,
J. Jirat, B. Kosata; updates compiled by A. Jenkins. ISBN 0-9678550-9-8.
https://doi.org/10.1351/goldbook.
